Alta Stomatology is an innovative oral disease research company dedicated to developing effective solutions for acute periapical periodontitis. Acute periapical periodontitis, also known as periradicular periodontitis, is a condition that develops when bacteria enter the apical portion of a tooth's tip, usually occurring after trauma or infection. At Alta Stomatology, we're dedicated to offering one-stop services for acute periapical periodontitis research, including whole-genome sequencing, the development of novel therapies, and the molecular mechanisms behind this disorder. If you have any needs, please feel free to contact us.

Fig.1 Acute periapical periodontitis radiograph (Alharbi OA, et al., 2019)

Research on Acute Periapical Periodontitis

Periapical periodontitis is an inflammatory disease that affects the tissues surrounding the root end of a tooth and is caused by infection of the root canal (endodontic). The disease can manifest itself in different clinical ways, including the development of an acute abscess. The acute abscess can be regarded as an advanced stage of the symptomatic form of apical periodontitis.

Non-surgical root canal therapy is the treatment of choice for periapical periodontitis and is used to eliminate or reduce the bacterial load inside the endodontium, thus resolving the inflammatory reaction and promoting healing of the periapical tissues. A possible beneficial effect of the use of statins on the inception and healing of AP has been suggested by recent literature. In dental field, administration of statins has shown a favorable effect in preventing alveolar bone loss in animal experimental periodontitis.

At the same time, dental stem cells have been successfully isolated from teeth and surrounding tissues, and they have shown great potential for clinical application. To date, many articles using dental stem cells have reported the treatment of pulpitis, periapical lesions, periodontitis, cleft lip and palate, acute ischemic stroke, and so on, and DSC-based therapies obtained satisfactory effects in most clinical trials.

Our Products

Our Services

At Alta Stomatology, we are committed to providing top-notch services in the field of oral disease research, specifically focusing on acute periapical periodontitis and and its prevention and treatment. Alta Stomatology actively engages in NsRCT research. For this purpose, we are committed to the research and development of statins and the isolation of DSC. Through comprehensive material characterization and testing, we aim to discover effective substances to prevent the development of periapical periodontitis and aid healing.

Analysis Services

Customized Research Services

With the accumulated rich R&D experience and leading technology platform, Alta Stomatology can provide customers with high-quality "one-stop" technical services. For acute periapical periodontitis diseases, we can offer a variety of customized research services, including: animal model establishment, drug screening & therapeutic efficacy testing, in vitro and in vivo study, novel drug delivery system, and oral organoid development.

Our Diagnosis Methods

At Alta Stomatology, we understand the importance of accurate diagnosis for effective treatment of acute periapical periodontitis. That's why we have developed cutting-edge diagnosis methods to guide the diagnosis and assessment of the severity of apical periodontitis disease.

• Organoid Development Service
• NDDS Development Service
• Animal Model Establishment Service