| Synonym: |
Amelogenin, X isoform, Leucine-rich amelogenin peptide, LRAP |
| Description: |
Amelogenin, X isoform/AMELX, also known as Leucine-rich Amelogenin peptide, or LRAP, and encoded by the gene AMELX/AMG/AMGX, is an important protein in the biomineralization of teeth. AMELX appears to regulate the formation of crystallites during the secretory stage of tooth enamel development. AMELX is a secreted extracellular matrix protein that has many isoforms. Interestingly mutations in the AMELX protein are associated with changes in enamel microstructure that are linked with severe dental disease, and the various isoforms of AMELX protein all aid in increasing enamel thickness of the developing tooth. |
| Species Reactivity: |
Porcine, mouse |
| Immunogen: |
Recombinant protein corresponding to mouse Amelogenin, X isoform/AMELX. |
| Physical Form: |
Rabbit polyclonal serum with 0.05% sodium azide. |
| Biological Source: |
Rabbit |
| Quality Level: |
100 |
| Antibody Form: |
Serum |
| Type: |
Primary antibodies |
| Clone: |
Polyclonal |
| Technique: |
Immunohistochemistry: suitable
Western Blot: suitable |
| Target Post-Translational Modification: |
Unmodified |
| Recombinant: |
Amelogenin, X isoform/AMELX, also known as Leucine-rich Amelogenin peptide, or LRAP, and encoded by the gene AMELX/AMG/AMGX, is an important protein in the biomineralization of teeth. AMELX appears to regulate the formation of crystallites during the secretory stage of tooth enamel development. AMELX is a secreted extracellular matrix protein that has many isoforms. Interestingly mutations in the AMELX protein are associated with changes in enamel microstructure that are linked with severe dental disease, and the various isoforms of AMELX protein all aid in increasing enamel thickness of the developing tooth. |
| Shipped: |
Wet ice |
| Application: |
Anti-amelogenin, X isoform/AMELX antibody is an antibody against amelogenin for use in western blotting & IHC. |
| Storage: |
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
