Health Topics

In regenerative medicine, mesenchymal stem cells (MSCs) have garnered extensive attention because of their self-renewal and multi-differentiation abilities. Dental pulp stem cells (DPSCs), a type of MSCs ... Read More

Amelogenin was initially discovered in developing enamel and is mainly synthesized and secreted by odontoblasts. It is a group of heterogeneous proteins with a unique and complex structure. Amelogenin can... Read More

Periodontitis is a chronic and destructive inflammatory disease that adversely affects the supporting structures of the teeth, including the gingiva, periodontal ligament, and alveolar bone. It impacts ap... Read More

The acquired salivary pellicle (ASP) is a fundamental element in the maintenance of oral health, first observed by Alexander Nasmyth in 1839. This organic film forms on the surface of teeth as a result of... Read More

Oral cancer is a significant global health concern, with over 300,000 new diagnoses and approximately 145,000 deaths each year, ranking it as the sixth most common cancer worldwide. Affecting primarily in... Read More

Noma, also known as cancrum oris, is a devastating, non-communicable disease that affects small children, particularly in some of the world's most impoverished regions. Historically, noma was once prevale... Read More

In recent years, the field of nanomedicine has seen a burgeoning interest in mesoporous silica nanoparticles (MSNs) as innovative therapeutic carriers. MSNs are celebrated for their ability to deliver a w... Read More

The human immune system is remarkably complex, serving as a powerful defense network against a multitude of pathogens. It is broadly classified into two main types: innate immunity and adaptive immunity. ... Read More

In the realm of cell communication, exosomes are tiny but mighty. First identified in the 1980s as secreted vesicles from reticulocytes, these extracellular vesicles have since been recognized for their p... Read More

The oral epithelium, the layer of cells lining the mouth, is a crucial component of the body's first line of defense against environmental threats and pathogens. Its integrity and function are maintained ... Read More

Oral health is a crucial component of our overall well-being, yet oral diseases like periodontitis, oral cancer, and endodontic infections remain significant challenges worldwide. Historically, treatment ... Read More

Saliva, an often-overlooked biological fluid, has the potential to revolutionize diagnostics due to its ease of collection, non-invasiveness, and rich content of biomolecules. With the advent of advanced ... Read More

Matrix metalloproteinases (MMPs) are a large family of Ca²⁺ and Zn²⁺-dependent proteolytic enzymes that play a crucial role in various physiological processes by cleaving the compone... Read More

Matrix metalloproteinases (MMPs)-a group of over 20 zinc-dependent proteases—have the fascinating capability to degrade different types of extracellular matrix (ECM) proteins. Among these MMPs, MMP12 st... Read More

The oral microbiota is essential in the human body. It's a complex ecosystem with bacteria, microeukaryotes, archaea, and viruses. There are more than 700 species of oral bacteria alone, making it the sec... Read More

Cancer is one of the leading causes of mortality worldwide. According to a 2020 report by GLOBOCAN, there were approximately 10.3 million deaths due to cancer and around 19.3 million new annual cases glob... Read More

Oral health has received increased focus with more attention paid to the oral cavity, as medicine advances continuously. It goes beyond dental aesthetics and disease prevention. Several research confir... Read More

Oral cancer is a significant global health issue, with a complex, multistep process involving numerous genetic and environmental factors contributing to its development. Potentially malignant disorders (PMD)... Read More

The human oral cavity is a complex and dynamic ecosystem teeming with microorganisms, including bacteria, fungi, protozoa, archaea, and viruses. This microbial community, organized in biofilms or plaques,... Read More

Salivary glands (SGs) are indispensable for oral health, facilitating lubrication, enzymatic digestion, and microbial defense through saliva secretion. However, dysfunction in SGs can occur due to aging, ... Read More

Silk fibroin (SF), a protein derived from the silk of various insects, has garnered significant attention for its potential applications in the field of tissue engineering. Leveraging its unique mechanica... Read More

Silk fibroin, a protein derived from the cocoon of the silkworm Bombyx mori and other arthropods, has emerged as a multifunctional biomaterial with significant applications across various fields, includin... Read More

If you have biological samples in your hand and need to observe them through TEM, how should they be preprocessed? Sample pretreatment is very critical and determines the effect and quality of the entire TEM observation. If the... Read More

Cancer remains a formidable global public health challenge due to its high mortality rates. Among various cancers, oral cancer is notable for its increasing prevalence and complexity. Oral squamous cell c... Read More

Head and neck squamous cell carcinoma (HNSCC), which notably includes oral squamous cell carcinoma (OSCC), stands as the sixth most commonly encountered cancer on a global scale, with approximately 600,00... Read More

Cytokeratins, also known as keratins, are typical intermediate filament proteins in epithelial cells, exhibiting high molecular diversity. As part of the epithelial cell cytoskeleton, cytokeratins are cru... Read More