| Component: |
Anti-Human CD4, FITC; Anti-Mouse CD25, APC; Anti-Human FoxP3, PE; Rat IgG2a Isotype Control, PE; Normal Rat Serum; Fixation/Permeabilization Concentrate (4×); Fixation/Permeabilization Diluent; Permeabilization Buffer (10×); FCM Lysing Solution (Fixative Free) (10×); Flow Cytometry Staining Buffer (1×) |
| Storage: |
Store at 2-8°C for at least 1 year. |
| Overview: |
Tregs, short for regulatory T cells, are a subset of T cells. They play a crucial role in maintaining immune homeostasis and tolerance. Tregs are characterized by the expression of the transcription factor Foxp3 and surface markers like CD4 and CD25. They exert their immunosuppressive functions through various mechanisms, such as direct cell-cell contact and the secretion of inhibitory cytokines like IL-11 and TGF-β. |
