| Target: |
IL-6 (Interleukin 6) |
| Binding Specificity: |
AA 27-55 |
| Reactivity: |
Human |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IL-6 antibody is un-conjugated |
| Application: |
Flow cytometry (FACS), immunohistochemistry (IHC), ELISA, western blotting (WB) |
| Purification: |
Antigen affinity purified |
| Immunogen: |
A portion of amino acids 27-55 from the human protein was used as the immunogen for this IL-6 antibody. |
| Isotype: |
Ig fraction |
| Format: |
Liquid |
| Buffer: |
In 1X PBS pH7.4 with 0.09% sodium azide. |
| Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
| Handling Advice: |
Avoid repeated freeze-thaw cycles. |
| Storage: |
- 20°C |
| Storage Comment: |
Aliquot the IL-6 antibody and store frozen at - 20°C or colder. |
| Alternative Name: |
IL-6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
This gene is responsible for producing a cytokine involved in inflammation regulation and the development of B cells. It's mainly synthesized at sites of both acute and chronic inflammation, where it's released into the bloodstream. Once there, it triggers an inflammatory response by interacting with the interleukin 6 receptor, alpha, leading to transcriptional changes. This gene's activity is linked to various inflammatory conditions, including susceptibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. |
