| Target: |
IL-6 (Interleukin 6) |
| Binding Specificity: |
AA 30-212 |
| Reactivity: |
Human |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IL-6 antibody is un-conjugated |
| Application: |
Immunohistochemistry (IHC), western blotting (WB) |
| Sequence: |
VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENN LNLPKMAEKD GCFQSGFNEE TCLVKIITGL LEFEVYLEYL QNRFESSEEQ ARAVQMSTKV LIQFLQKKAK NLDAITTPDP TTNASLLTKL QAQNQWLQDM TTHLILRSFK EFLQSSLRAL RQM |
| Cross-Reactivity: |
Human, Mouse, Rat |
| Characteristics: |
Polyclonal antibodies |
| Purification: |
Affinity purification |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human IL6 (NP_000591.1). |
| Isotype: |
IgG |
| Format: |
Liquid |
| Buffer: |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
| Handling Advice: |
Avoid freeze / thaw cycles. |
| Storage: |
- 20°C |
| Storage Comment: |
Store at - 20°C. |
| Alternative Name: |
IL6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
This genetic sequence encodes a cytokine crucial for inflammation regulation and B cell development. Furthermore, the protein it produces acts as a natural fever inducer in individuals with autoimmune disorders or infections. Its secretion primarily occurs at sites of inflammation, both acute and chronic, stimulating an inflammatory response through the interleukin 6 receptor, alpha. The activity of this gene is linked to various inflammatory conditions, including susceptibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Different transcript variants arise due to alternative splicing. |
| Molecular Weight: |
23 kDa |
