| Target: |
IL-6 (Interleukin 6) |
| Binding Specificity: |
Internal region |
| Reactivity: |
Human, mouse, rat |
| Host: |
Rabbit |
| Clonality: |
Polyclonal |
| Conjugate: |
This IL-6 antibody is un-conjugated |
| Application: |
ELISA, immunocytochemistry (ICC), immunofluorescence (IF), immunohistochemistry (IHC), western blotting (WB) |
| Specificity: |
IL6 Antibody detects endogenous levels of total IL6. |
| Predicted Reactivity: |
Bovine |
| Purification: |
The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific). |
| Immunogen: |
A synthesized peptide derived from human IL6, corresponding to a region within the internal amino acids. |
| Isotype: |
IgG |
| Format: |
Liquid |
| Concentration: |
1 mg/mL |
| Buffer: |
Rabbit IgG in phosphate buffered saline , pH7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Precaution of Use: |
This product contains sodium azide: a poisonous and hazardous substance which should be handled by trained staff only. |
| Storage: |
- 20°C |
| Storage Comment: |
Store at - 20°C. Stable for 12 months from date of receipt. |
| Expiry Date: |
12 months |
| Alternative Name: |
IL6 |
| Synonyms: |
BSF2, HGF, HSF, IFNB2, IL-6, Il-6, ILg6, Ifnb2, il6, CHIL-6, interleukin 6, interleukin-6, IL6, Il6, il-6, IL-6. |
| Background: |
This cytokine boasts a wide array of biological functions, serving as a potent trigger for the acute phase response. It plays a crucial role in guiding B-cell maturation into Ig-secreting cells and is pivotal in the differentiation of lymphocytes and monocytes. Its influence extends to B-cells, T-cells, hepatocytes, hematopoietic progenitor cells, and CNS cells. Integral for the development of T(H)17 cells, it also functions as a myokine, being released into the bloodstream post-muscle contraction. This release prompts increased fat breakdown and improved insulin resistance. Moreover, it stimulates the growth of myeloma and plasmacytoma and fosters nerve cell differentiation. |
| Molecular Weight: |
24 kDa |
