Antibodies play a crucial role in the immune system, and harnessing their potential for therapeutic purposes has become a cornerstone in modern medicine. At Alta Stomatology, our vision is to revolutionize oral disease treatment by discovering and developing lead antibody molecules that target specific oral pathogens and biomarkers. Our experienced team of researchers employs state-of-the-art technologies to discover antibodies that exhibit high specificity and efficacy against key pathogens associated with oral diseases. If you have any needs or questions regarding our lead antibody molecule discovery services, please feel free to contact us.
At Alta Stomatology, we offer comprehensive lead antibody molecule discovery services tailored to meet the unique needs of our clients. Our services include:
Antigen Preparation
Our experienced team at Alta Stomatology excels in the preparation of antigens crucial for antibody discovery. We provide a one-stop service from gene synthesis, and vector construction to protein expression and purification using various expression systems such as E. coli, Yeast, insect baculovirus, mammalian cells, and in vitro E.coli systems. We also offer innovative platforms like virus-like particles (VLPs), nanodisc, and nanoparticle platforms to enhance immunogenicity and antigen presentation.
Stable Cell Line Construction
Alta Stomatology provides services for the construction of stable cell lines, facilitating investigations in the antibody development process. Our lentivirus packaging and stable cell Service ensures the efficient expression and verification of target antigens.
Our Immunization services at Alta Stomatology are conducted in state-of-the-art facilities under stringent standards. We introduce the target antigen into host organisms, utilizing traditional models such as mice or rabbits. We also use non-animal-based systems. Yeast cells or mammalian cell lines, modified through advanced genomic techniques like RNA or DNA transfection with viral vectors or plasmids, are employed to ensure a diverse and comprehensive approach to antibody generation.
Once antibodies are generated, Alta Stomatology employs high-throughput screening techniques to screen and select a large pool of candidates. This phase is critical for identifying antibodies with the desired specificity and high affinity for the target antigen. Our cutting-edge screening methods enable us to efficiently select lead antibody molecules from numerous candidates, saving time and resources.
We conduct comprehensive functional testing, including antigen ELISA, cell-based FACS, and antigen SPR assays to evaluate the binding activity and affinity between antibodies and target antigens.
Alta Stomatology utilizes a wide range of advanced techniques and methodologies to drive the discovery of lead antibody molecules for oral disease applications. Some of our key techniques include:
Phage display technology
Recombinant protein expression
Hybridoma technology
Bioinformatics and computational modeling
High-throughput screening
Others
Our team of researchers and scientists has extensive expertise and experience in lead antibody molecule discovery and drug development.
By harnessing advanced tools and technologies, we can deliver lead antibody molecule discovery services to you with greater speed and efficiency.
At Alta Stomatology, we adhere to stringent quality control standards throughout the lead antibody molecule discovery process. We prioritize the purity, potency, and efficacy of the antibodies we develop, ensuring that they meet the highest standards for drug development.