The molecular genetics research platform at Alta Stomatology utilizes molecular biology and genetics methods to investigate the etiology, genetic basis, and gene-related therapeutic approaches for oral diseases. The oral diseases under study include but are not limited to, dental caries, periodontal diseases, salivary gland diseases, and oral cancer. Our researchers conduct studies in genomics, transcriptomics, proteomics, and metabolomics to understand the genetic basis and molecular mechanisms of oral diseases. They also employ gene editing technologies such as CRISPR-Cas9 to study the function of specific genes and identify gene variants associated with oral health or disease. Through these studies, we aim to gain a deeper understanding of the pathogenesis of oral diseases and provide new insights and approaches for future prevention, diagnosis, and treatment.

Our Fields of Molecular Genetics Research

One of our primary research focuses lies in elucidating the genetic determinants of periodontal diseases, including periodontitis and gingivitis. By leveraging state-of-the-art genomic technologies, such as single-nucleotide polymorphism (SNP) analysis and whole-exome sequencing, we aim to unravel the genetic variants contributing to periodontal susceptibility and severity. Furthermore, our research extends to exploring the role of epigenetic modifications, such as DNA methylation and histone acetylation, in modulating gene expression patterns associated with periodontal health and disease.

In addition to periodontal diseases, Alta Stomatology is dedicated to unraveling the genetic architecture of other oral conditions, such as dental caries, oral mucosal disorders, and oral cancers. Through integrative genomic analyses and systems biology approaches, we strive to identify key genetic pathways implicated in disease pathogenesis, thereby paving the way for targeted therapeutic interventions and precision medicine strategies.

What We Can Do

Laboratory Equipment

• Organoid Development Service
• NDDS Development Service
• Animal Model Establishment Service