Non-Odontogenic Tumors of the Jaw
Alta Stomatology is an innovative oral disease research company focused on non-odontogenic tumors of the jaw. Non-odontogenic tumors of the jaws are tumors that occur within the jaws but do not originate from odontogenic tissue, including osteoma, osteochondroma, osteoid osteoma, fibroblastic tumors, myeloid-derived malignant tumors, metastatic tumors of the jaw, etc. Alta Stomatology offers a one-stop service for non-odontogenic tumors of the jaw, covering histological analysis, immunohistochemical analysis, and the research of molecular mechanisms behind this disorder. If you have any needs, please feel free to contact us.
Fig.1 Dental CT displays the osteoid osteoma of the jaw in three views (Kammoun R., et al. 2022).
Research on Non-Odontogenic Tumors of the Jaw
Non-odontogenic tumors of the jaw are relatively rare, with complex causes and a wide variety. They can be divided into two types, benign tumors and malignant tumors.
Benign tumors mainly include osteoma, osteochondroma, osteoid osteoma, and some fibroblastic tumors. They have clear boundaries and grow slowly. Generally, they are asymptomatic or have mild symptoms, have little impact and rarely become malignant. However, if the tumor is large or in a special location and not treated in time, it may affect joint activities, compress nerves and blood vessels, or cause skeletal deformities.
Malignant tumors mainly include some fibroblastic tumors and myeloid-derived malignant tumors, with rapid growth and unclear boundaries. They can cause pain and swelling in the tumor area, and cause osteoporosis, osteolytic and osteogenic bone destruction. Currently, they are managed primarily through surgical removal, radiation therapy, and chemotherapy.
Our Products
Our Services
Due to the low incidence of non-odontogenic tumors of the jaw, there is limited knowledge of them and there may be missed diagnoses and misdiagnoses in the early stages of the disease. Imaging-guided minimally invasive therapeutic techniques, such as radiofrequency ablation, laser ablation, and cryoablation, have great prospects in the management of osteoid osteoma.
At Alta Stomatology, we are dedicated to providing comprehensive basic research services for non-odontogenic tumors of the jaw. Pathological and cytogenetic analysis helps to diagnose and classify these tumors and develop new targeted therapies.
| Pathological Analysis |
Cytogenetic Analysis |
- Histopathological analysis
- Immunocytochemical analysis
- Hematoxylin and eosin staining
|
- Direct sequencing
- Microscope observation
- Fluorescence in situ hybridization (FISH)
|
Analysis Services
- Polymerase Chain Reaction (PCR)
- Liquid Chromatography Mass Spectrometry (LC-MS)
- Electrophoresis Technology
- Enzyme Linked Immunosorbent Assay (ELISA)
Customized Research Services
With the accumulated rich R&D experience and leading technology platform, Alta Stomatology can provide customers with high-quality "one-stop" technical services. For non-odontogenic tumors of the jaw, we can offer a variety of customized research services, including animal model establishment, drug screening & therapeutic efficacy testing, in vitro and in vivo study, novel drug delivery system, and oral organoid development.
Animal Model Establishment
Drug Screening
In Vitro and In Vivo Study
Novel Drug Delivery System
Oral Organoid Development
Our Diagnosis Methods
At Alta Stomatology, we understand the importance of accurate diagnosis for effective treatment of non-odontogenic tumors of the jaw. That's why we have adopted cutting-edge diagnosis methods to guide the diagnosis and assessment of the severity of jaw disease.
| Diagnosis Methods |
Description |
| Radiography Examination |
We employ state-of-the-art radiography technology to obtain detailed images of the location of the lesion, type of lesion, etc., enabling our experts to accurately identify tumors occurring in the jaw. |
| 3D CT |
3D CT analysis tools provide a more complete picture of bone destruction and help to visualize large, significantly destructive lesions occurring in the jaws. |
| MRI Scan Test |
MRI scans have a high resolution for soft tissues and can show soft tissue lesions around the jaw, such as osteonecrosis of the jaw and soft tissue swelling. |
| Histological Diagnosis |
Histological examination is a gold standard for the diagnosis of many pathological diseases, for which staining is an essential component. Once the tissue sample has undergone fixation, processing, embedding, sectioning, and staining, it can undergo analysis through microscopy. |
References
- Kammoun R.; et al. Osteoid osteoma of the basilar border of the mandible: A diagnostic dilemma. Case Reports in Dentistry. 2022, 2179877.
- Langlie J.A. Diagnosis and management of craniofacial osteomas. Journal of Craniofacial Surgery. 2023, 34 (5): 1515-1521.
- Shaw S.E.; et al. Non-odontogenic tumors of the jaws. In StatPearls. StatPearls Publishing. 2023.
For research use only. Not
intended for any clinical use.
