Alta Stomatology is an innovative oral disease research company dedicated to developing effective solutions for odontoma. Odontomas are considered to be one of the most common odontogenic tumors, with most presenting in the first 2 decades of life without sex predilection. In general, they constitute 22% of all odontogenic tumors of the jaws. At Alta Stomatology, we're dedicated to offering one-stop services for odontoma research, including whole-genome sequencing, the development of novel therapies, and the molecular mechanisms behind this disorder. If you have any needs, please feel free to contact us.

Fig.1 A: Histology of a compound odontoma showing multiple diminutive teeth with well-developed and orderly relationships between the dentin and enamel material. B: Haphazard blending of odontogenic precursors, including dentin-like material, in this complex odontoma (Thompson LDR., 2019)

Research on Odontoma

Odontomas are classified as odontogenic tumors; however, due to their limited and slow growth, they are considered to be hamartomas in which all dental tissues are represented, rather than benign neoplasm. On the basis of gross, radiographic, and microscopic features, odontomas are sub-classified into compound odontoma (small toothlike structures) and complex odontoma (a conglomeration of dentin, enamel, and cementum). Compound odontomas are more common in the anterior maxilla, while complex odontomas are more common in the posterior mandible.

The etiology of odontoma is unknown, but genetic factors, family history, and environmental causes such as trauma and infection have been suggested. The radiographic findings of odontomas depend on their stage of development and degree of mineralization. The first stage is characterized by radiolucency due to lack of calcification. Partial calcification is observed in the intermediate stage, while in the third stage the lesion usually appears as radiopaque masses surrounded by radiolucent areas corresponding to the connective tissue histologically. Odontomas are generally asymptomatic, often associated with delayed eruption, or impaction of permanent teeth.

Our Services

At Alta Stomatology, we are committed to providing top-notch services in the field of oral disease research, specifically focusing on odontoma and and its prevention and treatment. In relation to many of the odontogenic lesions that arise in the jaws, an understanding of the process of normal odontogenesis is helpful in distinguishing pathology from the process of normal development.

Analysis Services

Customized Research Services

With the accumulated rich R&D experience and leading technology platform, Alta Stomatology can provide customers with high-quality "one-stop" technical services. For aodontoma disease, we can offer a variety of customized research services, including animal model establishment, drug screening & therapeutic efficacy testing, in vitro and in vivo study, novel drug delivery system, oral organoid development, and bioinformatics analysis.

Our Diagnosis Methods

At Alta Stomatology, we understand the importance of accurate diagnosis for effective treatment of odontoma. That's why we have developed cutting-edge diagnosis methods to guide the diagnosis and assessment of the severity of odontogenic tumor disease.

• Organoid Development Service
• NDDS Development Service
• Animal Model Establishment Service