| Description: |
Epidermal growth factor (EGF) is the prototypical member of the EGF protein family, known for its highly similar structural and functional properties. EGF comprises nine EGF-like domains and nine LDL-receptor class B repeats. The human form of EGF is a 6,045-Da protein, consisting of 53 amino acids and featuring three intramolecular disulfide bonds. Initially purified from the mouse submandibular gland, EGF has since been identified in various human tissues, including the submandibular and parotid glands. It is also present in human platelets, macrophages, urine, saliva, milk, and plasma. EGF functions as a growth factor, promoting the growth of various epidermal and epithelial tissues both in vivo and in vitro, as well as stimulating the proliferation of some fibroblasts in cell culture. Its effects include cellular proliferation, differentiation, and survival. |
| Purity: |
> 90% as determined by SDS-PAGE. |
| Protein Construction: |
A DNA sequence encoding the mature soluble form of human EGF (Asn 971-Arg 1023) was fused with the Fc region of human IgG1 at the N-terminus. |
| Expressed Host: |
HEK293 Cells |
| Species: |
Human |
| Shipping: |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
| Storage: |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Formulation: |
Lyophilized from sterile PBS, pH7.4. |
| Endotoxin: |
< 1.0 EU per μg of the protein as determined by the LAL method. |
