| Description: |
Neuregulin 1 (NRG1) is one of the four proteins in the neuregulin family that interact with the EGFR family of receptors. Initially identified as a 44-kilodalton glycoprotein, NRG1 binds to the NEU/ERBB2 receptor tyrosine kinase, enhancing its tyrosine phosphorylation. This trophic factor plays a significant role in neural development, neurotransmission, and synaptic plasticity. |
| Species: |
Human |
| Purity: |
> 95% as determined by SDS-PAGE. |
| Protein Construction: |
A DNA sequence encoding the Human NRG1 (Thr176-Lys246) was expressed with an N-terminal Met. |
| Endotoxin: |
< 10 EU per mg of the protein. |
| Formulation: |
Lyophilized from sterile 30% acetonitrile, 1/1000 TFA.
Normally 5% - 8% trehalose, mannitol, and 0.01% Tween80 are added as protectants before lyophilization. |
| Shipping Condition: |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
| Storage Conditions: |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles. |
| Expressed Host: |
E. coli |
