| Synonym(s): |
Fibroblast Growth Factor-8; FGF-8b; AIGF; HBGF-8 |
| Description: |
FGF-8 (FGF-8b) is a heparin-binding growth factor within the FGF family. These proteins are pivotal in prenatal development, postnatal growth, and tissue regeneration by promoting cellular proliferation and differentiation. FGF-8 has four known alternate spliced forms: FGF-8A, FGF-8B, FGF-8E, and FGF-8F. Human and murine FGF-8A and B are identical, while human and mouse FGF-8E and F are 98% identical. FGF-8 targets cells expressing FGF receptors, including mammary carcinoma cells.
Recombinant Human/Murine FGF-8 (FGF-8b) is a 22.5 kDa protein composed of 194 amino acid residues. |
| Purity: |
≥ 95% by SDS-PAGE gel and HPLC analyses |
| Source: |
E.coli |
| Accession #: |
P55075 |
| Predicted Molecular Mass: |
22.5 kDa |
| Entrez Gene IDs: |
2253 |
| AA Sequence: |
MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR |
| Endotoxin: |
Endotoxin level is < 0.1 ng/μg of protein (< 1 EU/μg) |
| Concentration: |
50 X |
| Culture Type: |
Mammalian cell culture |
| Cell Type: |
Neural Progenitor Cells |
| Classification: |
Serum-free |
| Shelf Life: |
12 Months |
| Tested For: |
Endotoxin, performance, sterility, mycoplasma |
