| Synonym(s): |
Epidermal Growth Factor; Urogastrone; URG |
| Description: |
EGF is a powerful growth factor that promotes the growth of different epidermal and epithelial cells. Moreover, EGF has been demonstrated to reduce gastric secretion and play a role in the healing of wounds. EGF exerts its effects through a receptor called c-erbB, a type I tyrosine kinase receptor. This receptor also interacts with TGF-α and VGF (vaccinia virus growth factor). Recombinant Murine EGF is a 6.0 kDa spherical protein composed of 53 amino acid residues, featuring 3 intramolecular disulfide bonds. |
| Purity: |
≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Source: |
E.coli |
| Accession #: |
P01132 |
| Entrez Gene IDs: |
13645 |
| AA Sequence: |
NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR |
| Cross Reactivity Cited in References: |
Bacteria, dog, guinea pig, human, mouse, pig, rat |
| Biological Activity: |
The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/mL, corresponding to a specific activity of ≥ 1 × 107 units/mg. |
| Calculated Molecular Weight: |
6 kDa |
| Endotoxin: |
Endotoxin level is < 0.1 ng/μg of protein (< 1 EU/μg) |
