Recombinant Rat EGF Protein

2-1-1-green-tea-extract-1

Recombinant Rat EGF Protein

Cat. No.: SPOLEO00017
Epidermal growth factor (EGF) is the prototypical member of the EGF protein family, known for its highly similar structural and functional properties. EGF comprises nine EGF-like domains and nine LDL-receptor class B repeats. The human form of EGF is a 6,045-Da protein, consisting of 53 amino acids and featuring three intramolecular disulfide bonds. Initially purified from the mouse submandibular gland, EGF has since been identified in various human tissues, including the submandibular and parotid glands. It is also present in human platelets, macrophages, urine, saliva, milk, and plasma. EGF functions as a growth factor, promoting the growth of various epidermal and epithelial tissues both in vivo and in vitro, as well as stimulating the proliferation of some fibroblasts in cell culture. Its effects include cellular proliferation, differentiation, and survival.
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Description: Epidermal growth factor (EGF) is the prototypical member of the EGF protein family, known for its highly similar structural and functional properties. EGF comprises nine EGF-like domains and nine LDL-receptor class B repeats. The human form of EGF is a 6,045-Da protein, consisting of 53 amino acids and featuring three intramolecular disulfide bonds. Initially purified from the mouse submandibular gland, EGF has since been identified in various human tissues, including the submandibular and parotid glands. It is also present in human platelets, macrophages, urine, saliva, milk, and plasma. EGF functions as a growth factor, promoting the growth of various epidermal and epithelial tissues both in vivo and in vitro, as well as stimulating the proliferation of some fibroblasts in cell culture. Its effects include cellular proliferation, differentiation, and survival.
Purity: > 95% as determined by SDS-PAGE.
Protein Construction: A DNA sequence encoding the rat EGF (Asn974-Arg1026) was expressed and purified with an initial Met.
Expressed Host: E. coli
Species: Rat
Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Formulation: Lyophilized from sterile PBS, pH7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.

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