Single-cell sequencing is a technology that can decipher individual cellular characteristics, reflecting cell heterogeneity and the crucial functional properties of small cellular subpopulations. It can elucidate more subtle differences between cells, reveal individual developmental and functional mechanisms with higher resolution, and detect or monitor the occurrence and progression of oral diseases with greater sensitivity. Alta Stomatology is a company dedicated to oral disease research. We offer single-cell sequencing services based on microfluidic chip technology to reveal the distribution and function of different cell types in oral tissues, the mechanisms underlying the occurrence and development of oral diseases, oral microbiome-host interactions, and provide unique and powerful technical support for translational medicine research and drug development. If you have any needs, please feel free to contact us.
Our Services
At Alta Stomatology, we can provide a range of single-cell sequencing services tailored to meet the diverse needs of our clients. Our cutting-edge technologies and rigorous methodologies ensure the accuracy and reliability of our results, empowering researchers to advance their understanding of oral diseases.
Single-Cell Transcriptome Sequencing
Transcriptome sequencing at the single-cell level offers a powerful means to elucidate the molecular underpinnings of oral diseases. By capturing the transcriptomic profiles of individual cells, we unravel the gene expression dynamics driving disease progression, identify novel biomarkers, and elucidate cellular pathways implicated in oral pathologies. Our state-of-the-art sequencing platform coupled with advanced bioinformatics analysis ensures high-throughput profiling of single-cell transcriptomes with unparalleled accuracy and sensitivity.
Single-Cell Immune Receptor Sequencing
The immune system plays a pivotal role in the pathogenesis and treatment of oral diseases, modulating inflammation, tissue repair, and immune surveillance. Our single-cell immune receptor sequencing service enables the comprehensive profiling of immune cell populations within oral tissues, shedding light on their antigen specificity, clonal diversity, and functional status. By unraveling the complexities of immune responses at the single-cell level, we empower researchers to develop targeted immunotherapies and precision medicine approaches for oral diseases.
Single-Cell Transcriptional Dynamics Detection
Our single-cell transcriptional dynamics detection service employs advanced computational algorithms to analyze temporal patterns of gene expression within individual cells, uncovering key regulatory mechanisms and signaling pathways. Whether tracking the effects of drug treatments or elucidating cellular responses to microbial challenges, our dynamic transcriptomic analysis provides invaluable insights into the molecular dynamics of oral diseases.
Workflow of Single-Cell Sequencing
Application of Single-Cell Sequencing
Research on the development and differentiation of oral stem cells
Analysis and identification of subpopulations of oral cells
Studies on systems biology and molecular mechanisms
Analysis of heterogeneity and microenvironment of oral tumors
Analysis of biomarkers and molecular typing of oral diseases
Pharmacological analysis and discovery of drugs for oral diseases
Why Choose Alta Stomatology?
- Flexible and Efficient One-Core Technology
Our ready-to-use, precision microfluidic technology improves single-cell separation efficiency, enabling high-throughput analysis of tens of thousands of cells per chip. This ensures rapid turnaround times and cost-effective solutions for our clients, without compromising on data quality or reliability.
Our instrument automation capabilities reduce human error and streamline the sequencing process, ensuring reproducible results and minimizing variability between experiments. This maximizes data quality and reliability, enabling robust and actionable insights into cellular heterogeneity and dynamics.
Our single-cell sequencing platform detects cell types that make up less than 1% of the entire cell population, greatly improving the ability to detect rare and low-abundance cell populations within oral tissues. This high sensitivity enables the identification of rare disease-associated cell subsets and facilitates the discovery of biomarkers for early diagnosis and precision medicine.
- One-on-One Project Custom
Our single-cell sequencing can be customized according to customer needs, with personalized analysis plans tailored to the specific research objectives of our clients. This ensures that each project is designed to maximize scientific insights and accelerate discoveries in oral disease research.
- Professional Data Analysis
Our bioinformatics analysis team boasts rich experience in data mining and interpretation, providing comprehensive insights into complex single-cell sequencing data. From quality control and normalization to differential expression analysis and pathway enrichment, our team employs advanced algorithms and statistical methods to extract biological information from raw sequencing data.
For research use only. Not
intended for any clinical use.
