Alta Stomatology is an innovative oral disease research company dedicated to developing effective solutions for squamous odontogenic tumor. Squamous odontogenic tumor is a rare benign, slow-growing and locally infiltrative neoplasm originating from the odontogenic epithelium. At Alta Stomatology, we're dedicated to offering one-stop services for squamous odontogenic tumor research, including whole-genome sequencing, the development of novel therapies, and the molecular mechanisms behind this disorder. If you have any needs, please feel free to contact us.

Fig.1 The tumor consists of multiple rounded and irregularly shaped islands of squamous epithelium set in fibrous stroma (Jones BE, et al., 2011)

Research on Squamous Odontogenic Tumor

Since its first publication in 1975, the squamous odontogenic tumor (SOT) remains the rarest odontogenic lesion. Squamous odontogenic tumor is a benign odontogenic tumor classified according to the World Health Organization (WHO) in 2005 as an epithelium odontogenic tumor. SOT occurs on average in the fourth decade of life with a slight predilection for males.

Clinically, SOT can be presented as an asymptomatic, slow growing, intrabony lesion with few clinical signs and symptoms. Nevertheless, mobility and displacement of teeth, swelling of alveolar process, and mild to moderate pain are the main findings. An equal distribution between maxilla and mandible with preference for posterior mandible and anterior maxilla is observed. Commonly, it is a central lesion with few cases occurring as peripheral lesions. The typical presenting complaint is of an asymptomatic swelling in the alveolar process. Affected teeth may be mobile and, rarely, mild discomfort is reported. A number of cases are incidental discoveries on routine dental radiographs.

Our Services

At Alta Stomatology, we are committed to providing top-notch services in the field of oral disease research, specifically focusing on squamous odontogenic tumor and and its prevention and treatment. Careful evaluation with immunohistochemical investigations, may prove rewarding in differentiating an SOT from other odontogenic neoplasms. Molecular profiling of odontogenic tumors helps to identify patients for neoadjuvant therapies and reduces postoperative morbidity.

Analysis Services

Customized Research Services

With the accumulated rich R&D experience and leading technology platform, Alta Stomatology can provide customers with high-quality "one-stop" technical services. For squamous odontogenic tumor disease, we can offer a variety of customized research services, including animal model establishment, drug screening & therapeutic efficacy testing, in vitro and in vivo study, novel drug delivery system, oral organoid development, and bioinformatics analysis.

Our Diagnosis Methods

At Alta Stomatology, we understand the importance of accurate diagnosis for effective treatment of squamous odontogenic tumor. That's why we have developed cutting-edge diagnosis methods to guide the diagnosis and assessment of the severity of odontogenic tumor disease. 

• Organoid Development Service
• NDDS Development Service
• Animal Model Establishment Service