Malignant Odontogenic Tumor
Alta Stomatology is a leading oral disease research company that specializes in odontogenic carcinoma. We can provide you with a one-stop service for histology and pathology research, molecular biology research, immunohistochemistry research, etc. At the same time, our scientists can also offer customized research services according to customer needs to promote the research process. We are the ideal partner for combating malignant odontogenic tumor and improving oral health on a global scale, please feel free to contact us.
Fig.1 Exemplar histology of the commonest malignant odontogenic tumours. (A) Ameloblastic carcinoma. (B) Primary Intraosseous Carcinoma NOS. (C) Clear Cell Odontogenic Carcinoma. (D) Ameloblastic Fibrosarcoma. (Marin C, et al., 2021)
Research on Malignant Odontogenic Tumor
Malignant odontogenic tumours (MOTs) arise either de novo from the tooth forming tissues, their developmental residues or from existing odontogenic epithelial or mesenchymal neoplasms in the jaws and malignant transformation of benign odontogenic tumours (OTs). Most MOTs are neoplasms consisting of malignant epithelium, including ameloblastic carcinoma and primary intraosseous squamous cell carcinoma (PIOSCC).
MOTs are a heterogeneous group of lesions that arise from the epithelial and/or mesenchymal remnants of the tooth germ or from a pre-existing odontogenic lesion such as a benign OT or an odontogenic cyst. Due to their low incidence, they remain poorly understood entities with respect to their cancer biology, clinical behaviour, management and long-term prognosis. In addition, their histopathological features significantly overlap with their benign counterparts, increasing the difficulty for the pathologist to reach a diagnosis, and with significant potential for misdiagnosis. Regarding the management of MOTs, surgical excision has been reported as the mainstay of treatment.
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Our Services
Malignant odontogenic tumors are a rare category of cancers that form in the tooth-producing tissues of the jaw. These tumors start in the cells that form the teeth and the jaw bone. They can cause symptoms such as swelling in the jaw, pain, loose teeth, and abnormal teeth development. There are different types, including ameloblastic carcinoma and clear cell odontogenic carcinoma.
We are pleased to offer comprehensive basic research services focused on malignant odontogenic tumor. Our team of experienced researchers and scientists is dedicated to advancing our understanding of malignant odontogenic tumor through cutting-edge experimental methodologies and techniques.
Alta Stomatology provides first-class services for diagnosis and treatment research of odontogenic carcinoma. Our experts utilize immunohistochemical staining techniques to assess the expression of specific genes and proteins, helping to elucidate the molecular profile of odontogenic carcinoma. We employ state-of-the-art molecular techniques to investigate the molecular pathways involved in OC development and progression.
Customized Research Services
Alta Stomatology offers a comprehensive range of customized research services to address the specific needs of clients aiming to combat dental diseases. Our services include but are not limited to:
Animal Model Establishment
Drug Screening
In Vitro and In Vivo Study
Novel Drug Delivery System
Oral Organoid Development
Bioinformatics Analysis
Why Choose Alta Stomatology?
- Cross-disciplinary Professional Team
Alta Stomatology has assembled a cross-disciplinary professional team, including clinical practitioners, scientists, researchers, and more in the field of oral health. This multidisciplinary collaborative approach enables the team to comprehensively and deeply investigate odontogenic tumor from various perspectives, ensuring the thoroughness and depth of the research.
The research team at Alta Stomatology possesses a wealth of expertise in the field of dentistry, with in-depth knowledge of oral anatomy, microbiology, biochemistry, and related disciplines. This allows them to have a comprehensive understanding of tooth structure and the oral environment, providing a solid foundation for delving into the pathogenesis of odontogenic tumor and drug development.
In the pursuit of unraveling the complexities of odontogenic tumor, Alta Stomatology harnesses cutting-edge technology and methodologies. From advanced imaging techniques to genomic analyses, our commitment to staying at the forefront of scientific innovation ensures that our research is both comprehensive and pioneering.
Reference
- Marin C, et al. Malignant Odontogenic Tumours: A Systematic Review of Cases Reported in Literature. Front Oral Health. 2021; 2:775707.
For research use only. Not
intended for any clinical use.
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