Alta Stomatology is a leading oral disease research company that specializes in pulpitis, pulp degeneration and necrosis, and tooth resorption research. We can provide you with a one-stop service for the development of filling materials, root canal filling materials, crown repair materials and pulp soothing materials. Our mission is to improve oral health worldwide by developing effective therapies for pulp diseases. We are the ideal partner for combating pulp diseases and improving oral health on a global scale, please feel free to contact us.
Fig.1 Schematic diagram highlighting the therapy of regenerative endodontics. (Kearney M, et al., 2018)
Research on Pulp Diseases
The pulp is the neurovascular bundle central to each tooth, permanent or primary. It is composed of a central pulp chamber, pulp horns, and radicular canals. The pulp is the connective tissue, nerves, blood vessels, and odontoblasts that comprise the innermost layer of a tooth. The pulp's activity and signaling processes regulate its behavior. The pulp has been described as a highly resistant organ and its resistance depends on cellular activity nutritional supply age, metabolic and physiologic parameters.
The pulp is the principal source of pain within the mouth and also the major site of attention in endodontics and restorative treatment. The causes of pulp disease include: physical, chemical and bacterial. There are several different pulp diseases, including: pulpitis, pulp degeneration and necrosis and tooth resorption. Depending on the type of pulp disease, symptoms may vary in intensity. If infected pulp in the tooth isn't cleared, a severe infection can spread to surrounding tissue, including the jaw bone. The main treatment method used clinically is root canal treatment.
Our Products
Bipolar Enamel-coated Stainless Steel Wire Electrode
Hematoxylin-eosin (HE) Staining Kit
Lipo-polysaccharide (LPS)
Rat Interleukin 1β (IL-1β) ELISA Kit
Tumor Necrosis Factor α (TNF-α) ELISA Kit
Streptococcus Mutans
Surgical Instruments for Laboratory
Growth Factor
Dental Pulp Stem Cell
Our Services
The pulp is surrounded by the hard dental tissues - dentine, enamel, and cementum - all of which help to protect the pulp from external stimuli. Once the enamel loses its integrity, and especially if the dentine is exposed, there is the potential for pulp irritation as a result of bacterial ingress through the defect. The pulp will eventually become inflamed (pulpitis) if the bacteria and/or caries are not eliminated and the pathway for their entry is left open (i.e., no dental treatment is performed). If this situation persists, the pulp will eventually necrotize as a result of the bacteria and/or caries spreading closer to the root canal.
Pulpitis research at Alta Stomatology focuses on the pulp hyperemia, acute pulpitis, and chronic pulpitis. Our team has rich experience in research and development of pulp soothing materials, root canal sealers, core obturation materials and other pulpitis treatment materials.
At Alta Stomatology, we are committed to providing top-notch services for the development of root canal filling materials, crown repair materials and biological scaffold materials to promote the diagnosis and treatment of pulp degeneration and necrosis. Through comprehensive materials characterization and testing, Alta Stomatology aims to discover effective pulp necrosis treatment materials to improve oral health worldwide.
Alta Stomatology specializes in developing root canal filling materials and core obturation materials for tooth resorption. By using these filling materials, the progression of the disease can be controlled in a timely manner. Therefore, effective filling materials are key to preventing and treating tooth resorption.
Customized Research Services
Alta Stomatology offers a comprehensive range of customized research services to address the specific needs of clients aiming to combat dental diseases. Our services include but are not limited to:
Animal Model Establishment
Drug Screening
In Vitro and In Vivo Study
Novel Drug Delivery System
Oral Organoid Development
Why Choose Alta Stomatology?
1. Customized and Scientific Support
Alta Stomatology offers multiple customized research services tailored to specific therapeutic needs. We provide technical support and collaborate closely with our clients to develop customized research plan and protocol.
2. Quality and Reliability
Alta Stomatology maintains a strong focus on the quality and reliability of research projects. We employ stringent quality control measures throughout the development process, from project design to data delivery.
3. Confidentiality and Intellectual Property Protection
We understand the importance of confidentiality and intellectual property protection. Alta Stomatology prioritizes the security and confidentiality of client information and maintains strict confidentiality agreements. We work closely with our clients to protect their intellectual property rights and ensure the confidentiality of their proprietary formulations and technologies.
References
- Singh G, et al. Disease of Pulp and Periradicular Tissue: An Overview. Journal of Current Medical Research and Opinion. 2020; 3(10): 652-664.
- Kearney M, et al. Epigenetic Approaches to the Treatment of Dental Pulp Inflammation and Repair: Opportunities and Obstacles. Front Genet. 2018; 9:311.
For research use only. Not
intended for any clinical use.
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