Alta Stomatology is a company specializing in the development of oral disease drugs. Due to the complex physicochemical environment within the oral cavity, such as saliva and food, which can affect the efficacy of free drugs, there is a need to develop a range of drug delivery systems to serve as carriers for active ingredients to promote antimicrobial properties, tissue regeneration, and drug diffusion engineering. These drug delivery systems can be used for the prevention and treatment of dental caries, periodontal disease, periapical disease, and the delivery of anesthetics, among others. Alta Stomatology has an oral disease drug delivery system research platform, which is equipped with advanced laboratory instruments and an experienced research team. We can develop drug delivery systems such as nanoparticles, hydrogels, nanofibers, and films to increase the solubility of oral disease medications, prolong the duration of drug action, enhance drug targeting, and reduce cytotoxicity.

Our Research

Alta Stomatology employs cutting-edge carrier materials, including nanoparticles, hydrogels, nanofibers, films, and scaffolds, to design highly effective drug delivery systems. These systems are tailored to overcome the barriers presented by the complex oral environment, optimizing drug loading and release kinetics. In addition, we can also evaluate the efficacy of drug delivery systems in preclinical models, and assess their biocompatibility and safety profiles.

Nanoparticles

Alta Stomatology utilizes both inorganic and organic nanoparticles to encapsulate oral disease drugs. These nanoparticles, such as mesoporous silica and calcium silicate nanoparticles, demonstrate excellent drug loading and release properties, making them ideal for treating conditions like dental caries and promoting tissue regeneration.

Hydrogels

Alta Stomatology utilizes natural and synthetic hydrogels to serve as 3D networks for drug delivery. These thermosensitive hydrogels are particularly promising for periodontal regeneration and anti-inflammatory applications, offering sustained release of drugs for extended therapeutic effects.

Nanofibers

Alta Stomatology harnesses the high surface area and porosity of nanofibers to carry antimicrobial agents and accelerate wound healing in oral tissues. Polymeric nanofibers, prepared through techniques like electrospinning, provide an efficient platform for localized drug delivery.

Films

Oral films developed by Alta Stomatology act as carriers for direct and gradual drug release, targeting conditions like oral candidiasis and providing local anesthesia. These mucoadhesive films offer a convenient and effective delivery method for patients.

What We Can Do

Laboratory Equipment

• Organoid Development Service
• NDDS Development Service
• Animal Model Establishment Service