Dental Caries

Dental Caries

Alta Stomatology is a leading oral disease research company that specializes in enamel, dentin, and root caries research, we can provide you with a one-stop service for the development of remineralizing agents, MMP inhibitors, antimicrobial agents, and other dental caries drugs. Our mission is to improve oral health worldwide by developing effective therapies for dental caries. We are the ideal partner for combating dental caries and improving oral health on a global scale, please feel free to contact us.

dental-caries

Research on Dental Caries

Dental caries, commonly known as tooth decay, is the most prevalent chronic oral disease worldwide. Dental caries research indicates that frequent consumption of carbohydrate-rich foods and the acidification of oral biofilms are the primary environmental pressures leading to caries. Environmental acidification alters the proportions of specific bacterial populations, triggering and exacerbating caries lesions. Acid-tolerant bacteria, such as S. mutans, thrive in low-pH environments, playing a crucial role in acid-induced corrosion. Therefore, the interaction between dietary patterns, frequency, and the composition of oral microbiota is a significant factor in the development of dental caries.

In the past years, significant progress has been made in the research of dental caries medications. The focus has been on novel antimicrobial agents, enamel remineralization, and biological repair. New antimicrobial agents, such as fluoride alternatives and antimicrobial peptides, have demonstrated superior anti-caries effects, reducing dependence on fluoride. Research on enamel remineralization aims to discover compounds that promote the repair of early caries damage. Biological repair strategies stimulate the regeneration of dental pulp stem cells through active ingredients, offering innovative approaches to caries treatment. These studies not only lay the foundation for the development of more effective caries medications but also hold promise for future personalized, biology-driven caries therapies.

Our Products

Amelogenin

Enamelin

Tuftelin

Streptococcus

Actinomyces

Lactobacillus

Bifidobacterium

Matrix Metalloproteinases

Type I collagen

Proteoglycan

Our Services

Dental caries is a multifactorial disease that results from the demineralization of tooth enamel by acids produced by bacteria in the mouth. These bacteria feed on sugars and starches from food and beverages, producing acids that erode the enamel and eventually lead to the formation of cavities in the teeth. If left untreated, dental caries can progress and affect deeper layers of the teeth, including the dentin and root surfaces, causing pain, infection, and even tooth loss.

Enamel Caries Research

Enamel caries research at Alta Stomatology focuses on developing innovative remineralizing agents to prevent and treat enamel decay. Services include inorganic, organic, and polymer enamel remineralizing agent development to enhance enamel health. we aim to develop novel remineralizing agents to strengthen enamel and prevent the onset of tooth decay.

Dentin Caries Research

Alta Stomatology specializes in dentin caries research, offering advanced drug development services. Their focus development of MMP inhibitors to preserve tooth structure, antimicrobial agents to eliminate cariogenic bacteria, and remineralizing agents to strengthen enamel and dentin layers.

Root Caries Research

Alta Stomatology specializes in developing innovative treatment methods and preventive measures for root caries. Our team has extensive experience in root caries research and drug development, allowing us to offer customized services tailored to the specific needs of our clients. This includes the development of fluoride, remineralizing agents, antibacterial agents, and innovative restorative materials.

Customized Research Services

Alta Stomatology offers a comprehensive range of customized research services to address the specific needs of clients aiming to combat dental diseases. Our services include but are not limited to:

Animal Model Establishment

Animal Model Establishment

 Drug Screening

Drug Screening

In Vitro and In Vivo Study

In Vitro and In Vivo Study

Novel Drug Delivery System

Novel Drug Delivery System

Oral Organoid Development

Oral Organoid Development

Bioinformatics Analysis

Bioinformatics Analysis

Why Choose Alta Stomatology?

Cross-Disciplinary Professional Team

Alta Stomatology has assembled a cross-disciplinary professional team, including clinical practitioners, scientists, researchers, and more in the field of oral health. This multidisciplinary collaborative approach enables the team to comprehensively and deeply investigate Dental Caries from various perspectives, ensuring the thoroughness and depth of the research.

Oral Field Expertise

The research team at Alta Stomatology possesses a wealth of expertise in the field of dentistry, with in-depth knowledge of oral anatomy, microbiology, biochemistry, and related disciplines. This allows them to have a comprehensive understanding of tooth structure and the oral environment, providing a solid foundation for delving into the pathogenesis of dental caries and drug development.

Cutting-Edge Technology

In the pursuit of unraveling the complexities of dental caries, Alta Stomatology harnesses cutting-edge technology and methodologies. From advanced imaging techniques to genomic analyses, our commitment to staying at the forefront of scientific innovation ensures that our research is both comprehensive and pioneering.

References

  1. Qiu W.; et al. Application of antibiotics/antimicrobial agents on dental caries. BioMed Research International. 2020, 2020.
  2. Burne R. A.; et al. Progress dissecting the oral microbiome in caries and health. Advances in Dental Research. 2012, 24(2): 77-80.
For research use only. Not intended for any clinical use.
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