Alta Stomatology is a leading oral disease research company that specializes in benign and malignant odontogenic tumor research. We can provide you with a one-stop service for histological analysis, immunohistochemical analysis, and molecular analysis, etc. Our mission is to improve oral health worldwide by developing effective therapies for odontogenic tumor. We are the ideal partner for combating odontogenic tumor and improving oral health on a global scale, please feel free to contact us.
Fig.1 MAPK/ERK signaling pathway mutations in odontogenic tumors (Guimarães LM, et al., 2021)
Research on Odontogenic Tumor
Odontogenic tumors (OT) of the jaw are a group of lesions that originate from remnants of epithelium or ectomesenchyme associated with teeth development. It ranges from hamartomas to true tumors. Like normal odontogenesis, the odontogenic tumors represent inductive interactions between odontogenic ectomesenchyme and epithelium. The fourth edition of WHO histological typing of odontogenic tumors classifies them as benign and malignant. Then, they are subdivided according to the cell of origin to epithelial, ectomesenchymal, or mixed.
OT are basically divided into two primary categories; malignant and benign but the etiology is unknown. The majority of benign odontogenic tumors seem to arise de novo, whereas the malignant odontogenic tumors may arise de novo but more often arise from their benign precursor. The classification of odontogenic tumors is essentially based on interactions between odontogenic ectomesenchyme and epithelium.
Our Products
AM-1 Cells
AM-3 Cells
Polyclonal Anti-GFP Antibody
Reverse Transcription Reagent
Hematoxylin and Eosin (H&E) Staining Kit
Cytokeratin 17
Cytokeratin 14
EpiTect Bisulfite Kit
Chromogen DAB
Silanized Slides
Desmin Antibody
Actin Antibody
QIAamp DNA Mini Kit
Vimentin Antibody
Pancytokeratin Antibody
Hair Cortex Keratin
QIAamp DNA FFPE Tissue Kit
FastGene Gel/PCR Extraction Kit
Beta-catenin
SureSelect Human All Exon V5 Kit
HMGA2 Break-apart Probes
Tissue-Tek
CAM 5.2
Our Services
Odontogenic tumors are uncommon lesions that originate from cells and tissues involved in odontogenesis and from their remnants. These tumors comprise a heterogeneous group of lesions ranging from hamartomatous ones to benign and malignant neoplasms. Odontogenic tumors are classified into epithelial, mesenchymal, and mixed epithelial and mesenchymal tumors based on the odontogenic tissue they mimic. Odontogenic tumor research services are fundamental to understanding the complexity of odontogenic tumors, enabling better diagnosis, treatment, prevention, and ultimately improved patient care and outcomes.
With extensive expertise in Epithelial Odontogenic Tumor research as well as an advanced platform, Alta Stomatology can provide services of histological analysis, immunohistochemical analysis, and molecular analysis. Alta Stomatology focuses on identifying better diagnostic methods, and understanding the molecular and cellular mechanisms involved in the development and progression of the tumors.
Alta Stomatology specializes in mixed odontogenic tumors research, offering the service for histology and pathology research, molecular biology research, and immunohistochemistry research. Our team has extensive experience in mixed odontogenic tumors research, allowing us to understand the biology and behavior of the tumors, and assess the efficacy of various treatment strategies.
Alta Stomatology has extensive experience in mesenchymal odontogenic tumor research, allowing us to provide the services of pathogenesis research, immunohistochemical analysis, molecular biology study, as well as customized research services based on our clients' specific needs. Our team has expertise in facilitating the evaluation of novel treatment strategies and exploring disease mechanisms.
Alta Stomatology provides first-class and comprehensive research services including bioinformatics, genomics, proteomics and cell biology. Through our services on genetic analysis, and protein expression study of odontogenic carcinoma samples, we can understand the genetic and molecular mechanisms, and develop more effective treatment strategies.
Alta Stomatology focuses on exploring the pathogenesis of bone related lesions to better prevent and treat it. Services include molecular analysis and protein expression study. These research services employ cutting-edge techniques such as next-generation sequencing, bioinformatics, molecular biology and cell culture, which aids in understanding genetic factors triggering these tumors, which can lead to more precise and personalized therapies.
Customized Research Services
Alta Stomatology offers a comprehensive range of customized research services to address the specific needs of clients aiming to combat dental diseases. Our services include but are not limited to:
Animal Model Establishment
Drug Screening
In Vitro and In Vivo Study
Novel Drug Delivery System
Oral Organoid Development
Bioinformatics Analysis
Why Choose Alta Stomatology?
1. Customized and Scientific Support
Alta Stomatology offers multiple customized research services tailored to specific therapeutic needs. We provide technical support and collaborate closely with our clients to develop customized research plan and protocol.
2. Quality and Reliability
Alta Stomatology maintains a strong focus on the quality and reliability of research projects. We employ stringent quality control measures throughout the development process, from project design to data delivery.
3. Confidentiality and Intellectual Property Protection
We understand the importance of confidentiality and intellectual property protection. Alta Stomatology prioritizes the security and confidentiality of client information and maintains strict confidentiality agreements. We work closely with our clients to protect their intellectual property rights and ensure the confidentiality of their proprietary formulations and technologies.
References
- Wright JM, Soluk Tekkesin M. Odontogenic tumors: where are we in 2017? J Istanb Univ Fac Dent. 2017; 51(3 Suppl 1):S10-S30.
- Guimarães LM, et al. The Molecular Pathology of Odontogenic Tumors: Expanding the Spectrum of MAPK Pathway Driven Tumors. Front Oral Health. 2021; 2:740788.
For research use only. Not
intended for any clinical use.
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