Alta Stomatology is a leading oral disease research company that specializes in osteomyelitis of jaws research. We can provide you with the service for histological analysis, immunohistological analysis, and microbiological diagnosis, etc. In addition, we offer custom research services that are critical to guiding osteomyelitis of jaws research efforts and developing targeted treatments. We are the ideal partner for combating osteomyelitis of jaws and improving oral health on a global scale, please feel free to contact us.

Fig.1 Four distinct histologic features of chronic nonbacterial osteomyelitis (Padwa BL, et al., 2016)

Research on Osteomyelitis of Jaws

The exact definition of osteomyelitis is inflammation of the osseous medulla. Most osteomyelitis in long bones arise from either local extension or hematogenous spread, but in maxillofacial skeleton, the spread is mostly by local extension from skin, oral cavity, or paranasal sinuses. It is a relatively uncommon complication in patients undergoing extraction with normal immune function status because of the perceived excellent vascularity in this region of the body. Highest rates of osteomyelitis are noted in patients with vascular insufficiency and immune dysfunction as well as in those with bone metabolic abnormalities.

Osteomyelitis of the jaw, a formerly frequent disease in developed countries, is now seldom encountered due to the development of antibiotics, improved oral hygiene, and better access to medical care. To date, it is composed of a variety of heterogeneous infections of the mandible and maxilla that mostly includes primary suppurative osteomyelitis of the jaw and infection complicating osteonecrosis following a cancer treatment. Various conditions such as oral surgery, cancer, traumatism, radiotherapy, bisphosphonate therapy, and immunodepression are known to be risk factors, but relevant new data on osteomyelitis are scarce due to low disease prevalence and disease heterogeneity.

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Osteomyelitis of the jaws refers to osteomyelitis (which is infection and inflammation of the bone marrow, sometimes abbreviated to OM) which occurs in the jawbone (i.e. maxilla or the mandible). Historically, osteomyelitis of the jaws was a common complication of odontogenic infection (infections of the teeth). Before the era of antibiotic, it was frequently a fatal condition.

Customized Research Services

Alta Stomatology offers a comprehensive range of customized research services to address the specific needs of clients aiming to combat dental diseases. Our services include but are not limited to:

Why Choose Alta Stomatology?

• Cross-disciplinary Professional Team

Alta Stomatology has assembled a cross-disciplinary professional team, including clinical practitioners, scientists, researchers, and more in the field of oral health. This multidisciplinary collaborative approach enables the team to comprehensively and deeply investigate osteomyelitis of jaws from various perspectives, ensuring the thoroughness and depth of the research.

• Oral Field Expertise

The research team at Alta Stomatology possesses a wealth of expertise in the field of dentistry, with in-depth knowledge of oral anatomy, microbiology, biochemistry, and related disciplines. This allows them to have a comprehensive understanding of jaw structure and the oral environment, providing a solid foundation for delving into the pathogenesis of osteomyelitis of jaws.

• Cutting-Edge Technology

In the pursuit of unraveling the complexities of osteomyelitis of jaws, Alta Stomatology harnesses cutting-edge technology and methodologies. From advanced imaging techniques to genomic analyses, our commitment to staying at the forefront of scientific innovation ensures that our research is both comprehensive and pioneering.

• Organoid Development Service
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• Animal Model Establishment Service